AI Seminar, 11.06.2003, 10-12, glasburen

Krzysztof Pawlowski, AstraZeneca, Lund

Bioinformatics / computational biology in pharmaceutical industry

Abstract:

An overview of the role of bioinformatics in pharmaceutical industry
will be given from the perspective of a drug target discovery
scientist.  Typical applications of bioinformatics in pharma industry
will be briefly presented, together with challenges for the future.

* protein and nucleotide sequence analysis problems (e.g. gene
  prediction, protein structure prediction, function prediction), 
* gene expression microarray data analysis (e.g. reduction of
  dimensionality of data space, detecting disease-associated genes and
  classification problems)
* analysis of gene networks (e.g. extracting networks from biological
  and literature data; combining interaction networks originating from
  different data sources) 
* other systems biology approaches (e.g. whole cell simulations)